News

In a recent publication (Su and coworkers, X-ray Mediated Release of Molecules and Engineered Proteins from the Surface of Nanoparticles, 2018) the Guo and Siegel Labs presents unprecedented efficient release of modified green fluorescent proteins (GFP) from the surface of silica-coated gold nanoparticles.

In a recent publication (Su and coworkers, X-ray Mediated Release of Molecules and Engineered Proteins from the Surface of Nanoparticles, 2018) the Guo and Siegel Labs presents unprecedented efficient release of modified green fluorescent proteins (GFP) from the surface of silica-coated gold nanoparticles.

In a recent publication (Jenkins et al. Ultrafast Spintronics: Dynamics of the Photoisomerization-Induced Spin–Charge Excited-State (PISCES) Mechanism in Spirooxazine-Based Photomagnetic Materials), the Larsen Lab, in collaboration with the Frank Lab (U. Victoria) explored the primary photodynamics of a novel Co coordination complex that via the structural evolution of a modified spirooxazine ligand will induced long living spin states.

In a recent publication in Angewandte Chemie, the Cramer group and collaborators use a synchrotron technique, NRVS, to probe the coupling between the hydrogenase H-cluster and its neighboring proton transfer chain. NRVS is a vibrational spectroscopy that is only sensitive to the motions of the resonant nucleus, in this case 57Fe vibrations.

In a recent publication (Farahvash and Stuchebrukhov, The Journal of Physical Chemistry: B, 2018) the Stuchebrukhov Lab use Dowser++ (a protein hydration program designed by the group) to illustrate that the mitochondrial enzyme cytochrome c oxidase (CcO) permits a significantly higher hydration state than is seen in x-ray crystal structures. Analyzing the dynamic nature of these waters with MD simulations leads to several interesting results.

In a recent publication (Tantillo, Sarpong and coworkers, JACS, DOI: 10.1021/jacs.8b05804), results from calculations carried out by Stephanie Hare in the Tantillo lab shed light on the origins of selectivity for a synthetically useful carbocation rearrangement developed by the Sarpong lab at UCB.

Cholangocarcinoma is a highly prevalent form of cancer in Southeast Asia and primarily Thailand. It is caused by eating a river fish infected with a liver fluke that may eventually cause a form of liver cancer. A recent publication in the journal Oncogene (Nature Press) by collaborators in the Khon Kaen School of Medicine in Thailand and UC Davis Chemistry showed that metastasis is mediated by O-GlcNAcylation, a post-translational modification of proteins, through the proteins FOXO3 and MAN1A1.

Gas absorption calorimetry was customized to determine the energetics of H2O and CO2 absorption on zeolite A as a function of loading from near zero coverage to saturation, Results provide clear thermodynamic evidence of structural flexibility induced by guest molecules and identify diffe

A combined effort between the Larsen and Lagarias labs resolved the underlying heterogeneity of the photocycle initiation dynamics of the Cph1 phytochrome photoreceptor that strongly affects kinetics, absorption, fluorescence, and quantum yields (both photochemical and fluorescent) and implicates how structural rearrangements can affects in vivo function.