Olson Lab Research Featured on the Cover of ACS Chemical Neuroscience

Bryostatin image from Dr. David Olson's ACS Chemical Neuroscience feature cover
ACS Chemical Neuroscience cover featuring Dr. David Olson's work

In a recent publication, the Olson Lab used a variety of chemical tools to demonstrate that the marine natural product bryostatin 1 increases synaptogenesis while simultaneously reducing the number of protrusions that harbor synapses.  This unique effect has the potential to improve signal-to-noise ratio in the central nervous system and could possible explain why the natural product improves memory.  Bryostatin 1 is currently being investigated for the treatment of Alzheimer’s disease.

Bryostatin 1 image

More information at https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.0c00175