Olson Lab Research Featured on the Cover of ACS Chemical Neuroscience

In a recent publication, the Olson Lab used a variety of chemical tools to demonstrate that the marine natural product bryostatin 1 increases synaptogenesis while simultaneously reducing the number of protrusions that harbor synapses.  This unique effect has the potential to improve signal-to-noise ratio in the central nervous system and could possible explain why the natural product improves memory.  Bryostatin 1 is currently being investigated for the treatment of Alzheimer’s disease.

More information at https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.0c00175