![Crystal structure of HydE bound to Complex-B](/sites/g/files/dgvnsk196/files/styles/sf_landscape_16x9/public/media/images/Screenshot%202021-05-29%2010.18.27.png?h=40b419c5&itok=A741dq5y)
Crystal Structure of the [FeFe]-Hydrogenase Maturase HydE Bound to Complex-B
The collaboration of the Britt and Rauchfuss (UIUC) labs with the Nicolet group at Grenoble has revealed the structure of the Fe(II)(CO)2(CN)cysteine organometallic product of the HydG Fe-Fe hydrogenase “maturase” enzyme as bound and activated towards dimerization by HydE, the second radical SAM maturase enzyme in the hydrogenase H-cluster biosynthetic pathway.
Further information available at: https://pubs.acs.org/doi/pdf/10.1021/jacs.1c03367